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The values were expressed as mean ± standard error of the mean (SEM). *p < 0.05, **p < 0.01 and ***p < 0.001 Significant comparison to control group. #p < 0.05 Significant comparison to CFA 5.0 group. CFA 10.0 group demonstrated a significant gradual reduction in thermal withdrawal threshold, indicating the gradual development of thermal hyperalgesia throughout the experiment.
