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. 2021 Dec 8;16(12):e0260423. doi: 10.1371/journal.pone.0260423

Fig 6. Changes in rats’ ankle joint (a) circumferences and (b) diameter at the ipsilateral (CFA-inoculated) hind paw in the treatment groups on day 0 to 20 (n = 6).

Fig 6

The data are expressed as mean ± standard error of the mean (SEM). *p < 0.05 and **p < 0.001 significant comparison to control group. ###p < 0.001 significant comparison to CFA 5.0 group and §§§p < 0.001 significant comparison to CFA 7.5 group. CFA 10.0 group demonstrated the most reliable and constant gradual increase in the ankle joint oedema at the ipsilateral side compared to other doses of CFA inoculation.