Table 2.
A comparison of demographics, allergic history, and self-reported symptoms after the first dose of the Pfizer-BioNTech vaccine in the patients recommended for full-dose, graded-dose protocol or deferral*
Two-step graded-dose protocol for the second dose of the Pfizer-BioNTech vaccine, defined as the administration of 0.05 mL, followed by 0.25 mL intramuscular injection in the same arm, with 30 minutes in between doses; all patients who underwent the graded-dose protocol remained under an allergist's observation for a minimum of 60 min after vaccination.
#Symptoms included pruritus, dermatographism, shortness of breath, throat swelling sensation, dizziness, palpitations, or tightness in the fingers. One patient underwent a three-step graded protocol with 0.05 mL, 0.125 mL, and 0.125 mL doses.
§Value represents a sum of level of care for observation by a physician, primary care physician, urgent care, and emergency department.