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. 2021 Dec 6;28(1):2582–2593. doi: 10.1080/10717544.2021.2009936

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© 2021 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 6. — MMs-coated biomimetic nanoparticles can improve the therapeutic efficacy of ALI in a mouse model. (A) Experimental protocol for evaluating the therapeutic effect of free CEP, CEP/NLCs and MM-CEP/NLCs. (B) Total cell counts in BALF. (C) Lung water content was assessed by the measurement of wet-to-dry ratio. (D) Protein contents in BALF were measured using a BCA kit. (E) TNF-α and (F) IL-6 in BALF were measured by ELISA kit. (G) Hematoxylin and eosin (H&E)-stained lung tissue sections were imaged (scale bar = 100 μm). (n = 4, mean ± SD, *p < .05, **p < .01, ***p < .001 and ns, no significance).