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. 2021 Dec 6;60(1):25–37. doi: 10.1080/13880209.2021.1990969

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© 2021 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 1. — Histological sections from some experimental groups of rats as stained by haematoxylin and eosin (H &E). A, B, and C were taken from control, control + ellagic acid (EA), and control + EA + compound C (CC/AMPK inhibitor), respectively and showing normal liver architectures with rounded normally-appeared hepatocytes (long arrow) radiating from the central vein (CV) with intact sinusoids (short arrow). D was taken from an STZ-diabetic rat (T1DM-induced rat) and showed severe cytoplasmic accumulation of lipid vacuoles of different sizes including large (long arrow), medium (short arrow), and small (arrowhead) vacuoles. 200×.