Table 4.
ANOVA evaluation of best fitted quadratic model for vesicle size and entrapment efficiency.
| Source | Vesicle size (Y1) |
Entrapment efficiency (Y2) |
||||||
|---|---|---|---|---|---|---|---|---|
| Sum of squares | df | F Value |
p Value Prob>F |
Sum of squares | df | F Value |
p Value Prob>F |
|
| Model | 68658.83 | 14 | 575.39 | <.0001 | 2076.57 | 14 | 568.11 | <.0001 |
| A: surfactant (Span 60) | 13240.37 | 1 | 1553.45 | <.0001 | 511.97 | 1 | 1960.92 | <.0001 |
| B: CHOR | 37985.85 | 1 | 4456.76 | <.0001 | 1337.37 | 1 | 5122.34 | <.0001 |
| C: bile salt | 3005.04 | 1 | 352.57 | <.0001 | 173.72 | 1 | 665.39 | <.0001 |
| D: PEG-2000 | 2562.84 | 1 | 300.69 | <.0001 | 9.97 | 1 | 38.21 | <.0001 |
| AB | 4944.13 | 1 | 580.08 | <.0001 | 4.23 | 1 | 16.18 | .0017 |
| AC | 16 | 1 | 1.87 | .1957 | 9.42 | 1 | 36.07 | <.0001 |
| AD | 48.81 | 1 | 5.73 | .0339 | 9.02 | 1 | 34.54 | <.0001 |
| BC | 135.21 | 1 | 15.86 | .0018 | 0.14 | 1 | 0.54 | .4751 |
| BD | 16.12 | 1 | 1.89 | .1941 | 1.58 | 1 | 6.05 | .0300 |
| CD | 2432.46 | 1 | 285.39 | <.0001 | 0.52 | 1 | 2.01 | .1814 |
| A 2 | 1382.57 | 1 | 162.21 | <.0001 | 16.2 | 1 | 62.13 | <.0001 |
| B 2 | 1130.33 | 1 | 132.61 | <.0001 | 6.07 | 1 | 23.26 | .0004 |
| C 2 | 330.39 | 1 | 38.76 | <.0001 | 6.08 | 1 | 23.31 | .0004 |
| D 2 | 236.08 | 1 | 27.69 | .0002 | 4.39 | 1 | 16.85 | .0015 |
| Residual | 102.27 | 12 | – | – | 3.13 | 12 | – | – |
| Lack of fit | 83.61 | 10 | 0.8958 | .6349 | 2.93 | 10 | 2.95 | .2791 |
| Pure error | 18.66 | 2 | – | – | 0.19 | 2 | – | – |
| Cor total | 68761.11 | 26 | – | – | 2079.70 | 26 | – | – |