Table 5.

A summary of COVID-19 drug effectiveness meta-analyses.

Drug	No. patients	Outcome	Effect
Vitamin D (Rawat et al., 2021)	467	Mortality reduction	No effect; R = 0.55 (95 % CI 0.22–1.39), p = 0.21
HCQ (Amani et al., 2021)	6059	Mortality reduction	No effect, RR = 0.7 (95 % CI: 0.24–1.99)
HCQ (Bartoszko et al., 2021)	8161	Side effects	RR = 1.81 (95 % CI: 1.36–2.42), p < 0.05
HCQ (Axfors et al., 2021)	10,012	Increase of mortality	OR = 1.11 (95 % CI: 1.02–1.20)
Convalescent plasma (Bansal et al., 2021b)	27,706	Mortality reduction	OR 0.76 (95 % CI: 0.53–1.08), p = 0.13
Sarilumab (Lescure et al., 2021b)	416	Positive effect	HR = 1.03 (95 % CI 0.75–1.40]; p = 0.96

Legend: HCQ – hydroxychloroquine; HR – hazard ratio; OR – odds ratio; RR – risk ratio; 95 % Cl – 95 % confidence interval.