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. 2021 Dec 9;39(1):1–21. doi: 10.1007/s40266-021-00909-8

Table 8.

Age of patients included in industry-funded pivotal trials and largest post-marketing studies in Tables 1, 2, 3, 4, 5 and 6

References Age, years; median or mean (range)
Investigational arm Standard/placebo arm
Marty et al. [78] Median 57 (29–69) Median 57 (29–69)
Bonneterre et al. [79] No data No data
Kaasa et al. [80] Median 58 (19–80) Median 58 (19–80)
Marschner et al. [81] Median 55 (28–79) Median 53 (29–77)
Warr et al. [84] Median 57 (no data) Median 55 (no data)
Perez et al. [85] Mean 55 (18–87) Mean 56 (21–94)
Gralla et al. [86] Mean 62 (19–87) Mean 62 (20–88)
Gralla et al. [88] Mean 56 (no data) Mean 55 (no data)
Eisenberg et al. [89] Mean 53 (no data) Mean 54 (no data)
Aapro et al. [90] Mean 53 (no data) Mean 51 (no data)
Saito et al. [91] Mean 58 (no data) Mean 58 (no data)
Navari et al. [97] Mean 64 (no data) Mean 60 (no data)
Chawla et al. [101] Mean 56 (no data) Mean 54 (no data)
Hesketh et al. [102] Mean 59 (no data) Mean 58 (no data)
Poli-Bigelli et al. [103] Mean 54 (no data) Mean 53 (no data)
Warr et al. [105] Mean 53 (no data) Mean 52 (no data)
Hesketh et al. [109] Median 53 (19–77) Median 55 (no data)
Aapro et al. [110] Median 54 (22–79) Median 54 (no data)
Gralla et al. [112] Median 57 (27–76) Median 59 (no data)
Rapoport et al. [115] Median 56 (20–75) Median 54 (18–77)
Rapoport et al. [116] Median 59 (21–86) Median 59 (18–90)
Schwartzberg et al. [117] Median 58 (22–86) Median 56 (22–88)