Table 4.
Changes in Serum CRP Levels Among Syphilitic Patients with and without the JHR After Benzathine Penicillin Treatment
| No JHR Before Treatment | JHR Before Treatment | Mann–Whitney U-Test (p-value) 95% CI | No JHR After Treatment | JHR After Treatment | Mann–Whitney U-Test (p-value) 95% CI | |
|---|---|---|---|---|---|---|
| All syphilitic patients (N=29) | ||||||
| N=17 | N=12 | N=17 | N=12 | |||
| CRP | ||||||
| Median | 3488.6 | 16,262 | 0.0059 | 4328 | 16,159 | 0.0051 |
| IQR | 924–16,064 | 12,032–26,150 | 4002 ~ 17,098 | 482–13,328 | 9352–24,561 | 3954 ~ 17,401 |
| HIV-infected syphilitic patients (N=21) | ||||||
| N=14 | N=7 | N=14 | N=7 | |||
| CRP | ||||||
| Median | 3280.2 | 14,953.6 | 0.0556 | 3712.6 | 18,131.4 | 0.0309 |
| IQR | 1080–18,732 | 11,761–27,160 | −1808 ~ 17,637 | 527–15,555 | 9003–25,183 | 667 ~ 20,300 |
Abbreviations: CRP, C-reactive protein; JHR, Jarisch-Herxheimer reaction; IQR, interquartile range; HIV, human immunodeficiency virus.