Table 1.
Plasma organic acid concentrations measured by anion analysis in rats.
| Metabolites (μM) | Control | Citric acid | P value |
|---|---|---|---|
| Lactate | 2129 ± 120 | 1914 ± 163 | 0.31 |
| Citrate∗∗∗ | 61.7 ± 4.1 | 126 ± 12.7 | P < 0.001 |
| cis-Aconitate∗∗∗ | 2.9 ± 0.2 | 6.0 ± 0.6 | P < 0.001 |
| Isocitrate∗∗∗ | 5.7 ± 0.3 | 9.2 ± 0.7 | P < 0.001 |
| α-ketoglutarate | 23.2 ± 1.2 | 26.9 ± 1.3 | 0.054 |
| Succinate | 4.9 ± 0.4 | 4.2 ± 0.3 | 0.19 |
| Fumarate | 1.4 ± 0.1 | 1.5 ± 0.1 | 0.36 |
| Malate | 31.8 ± 3.1 | 37.3 ± 2.4 | 0.18 |
| Pyroglutamate∗∗ | 26.2 ± 2.8 | 13.6 ± 2.7 | 0.006 |
| Pantothenate | 0.8 ± 0.1 | 0.6 ± 0.0 | 0.19 |
Data are expressed as mean ± standard error (SE) of eight rats.
Values are significantly different from that of the control group at ∗∗P < 0.01, ∗∗∗P < 0.001.