Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Dec 8;11:23622. doi: 10.1038/s41598-021-01655-y

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Bundle representation of furin cleavage site and correspondence scatter plot. The left panel shows the one-to-one comparison of sequence MSA of the furin cleavage sites of different coronaviruses. The 20 amino acids of the furin cleavage motif are depicted by different colors on the top of the sequence alignment logo (P stands for the position). The color scheme of fonts is based on reference³⁸. Amino acids are sorted based on their biochemical properties. Each continuous line represents a sequence in the alignment. The red line is the sequence of the Sgp_SARS-CoV-2 furin cleavage site. The lower panel shows the correspondence scatterplot and a close look at the selected correspondence sites (left and right panels, respectively). The corresponding residues are in black boxes in the sequence of Sgp_SARS-CoV-2 on the left panel. X and Y axes are the first and second principal components, respectively.