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. 2021 Dec 8;11:23622. doi: 10.1038/s41598-021-01655-y

Table 3.

Correspondence analysis. Introducing the key residues in each domain.

Domain (total number of nonredundant sequences) Association Secondary content Occurrence Sequences
16–305 NTD (85) F32, T33 Coil Once, 1.18% A0A0U1WJY8 (BtRs-BetaCoV/YN2013), A0A1W5YKT9 (Bat coronavirus, UC)
330–521 RBD (230) T500, N501 Coil, Coil 39 (45.88), 6 (7.06)
522–907 (1898) NA
660–700 (Furin cleavage motif: 194) Q675, Q677, T678, A684 Coil, Coil, Coil, Extended strand Once (0.52%)
908–985 HR1 (937) NA
986–1035 CH (344) E990, Helix 6 (1.74%) A0A0P0INJ4 (SARS-like coronavirus BatCoV/BB9904/BGR/2008), D2DJW4 (SARS coronavirus Rs_672/2006), A0A0U1WHK9 (BtRf-BetaCoV/HeN2013), Q6R7Y6 (SARS coronavirus NS-1)
1076–1141 CD (34) NA