Table 1.
Demographic and epidemiological description of the cohort.
| Variables | N total | Mean | SD |
|---|---|---|---|
| Average age at the time of the LP (years ± SD) | 331 | 37.67 | 15.58 |
| N total | Frequency | ||
| Gender (female/male) | 331 | 143/188 | |
| A family history of psychiatric disorders | 315 | 147/315 (46.7%) | |
| Illegal substance abuse | 324 | 79/324 (24.4%) | |
| Alcohol abuse | 322 | 74/322 (23%) | |
| Cannabis abuse | 324 | 81/324 (25%) | |
| Tobacco abuse | 322 | 148/322 (46%) | |
| Diagnosed with rheumatic, infectious, oncologic, or CNS disease | 329 | 63/329 (19.1%) | |
| Diabetes type II | 328 | 18/328 (5.5%) | |
| Thyroid disease | 329 | 45/329 (13.7%) | |
| N total | Mean | SD | |
| Duration of illness at the time of the LP (months ± SD) | 277 | 71.96 | 102.59 |
| N total | Frequency | ||
| FEP at time of LP | 320 | 128/320 (40%) | |
| Recurrent psychotic episode | 320 | 192/320 (60%) | |
| Clozapine lifetime treatment | 331 | 68/331 (20.5%) | |
| Any cMRI alteration(s) | 313 | 173/313 (55.3%) | |
| White matter lesion | 313 | 109/313 (34.8%) | |
| Atrophy | 313 | 24/313 (7.7%) | |
| Tumor | 313 | 11/313 (3.5%) | |
| Other | 313 | 91/313 (29.1%) |
cMRI cerebal magnetic resonance imaging, CNS central nervous system, FEP first-episode psychosis, LP lumbar puncture, SD standard deviation.