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. 2021 Dec 8;7:380. doi: 10.1038/s41420-021-00773-w

Fig. 2. CRTC1 deficiency exaggerates blood–brain barrier breakdown and mice forelimb recovery after ischemia.

Fig. 2

A Representative TTC staining images of CRTC1 KO and WT mice brain sections 24 h after MCAO. B Quantification of infarct volume of CRTC1 KO and WT mice. n = 10 for each group. C Cerebral blood flow (CBF) pictures of CRTC1 KO and WT mice before and after MCAO. D Quantification of relative CBF change of right/left MCA responsible area. n = 10 for each group. Representative images (E) and quantification (F) of Evans Blue extravasation in CRTC1 KO and WT mice brains after MCAO. n = 4 for each group. Mice behavior deficits 24 h after MCAO were examined by Neurological Score (G) and Foot fault Test (H). n = 29 for WT, n = 26 for CRTC1 KO.