Table 3.
Summary of all MTR measurements in HCs and people with RRMS at each anatomical location.
PNS anatomical location | MTR Measurement [a.u.] [mean (±SD)] | p | |
---|---|---|---|
HC (N = 11) | RRMS (N = 15) | ||
Sciatic nerve | 35 (±3.2) | 32.4 (±3.6) | 0.027* |
Lumbar plexus | 28 (±1.7) | 28.8 (±1.7) | 0.43 |
Preganglionic regions | 24.7 (±2.8) | 26.1 (±3.4) | 0.47 |
Ganglionic regions | 28.9 (±2.4) | 29.4 (±1.8) | 0.39 |
Postganglionic regions | 30.3 (±1.7) | 30.8 (±2.5) | 0.91 |
PNS, peripheral nervous system; MTR, magnetisation transfer ratio; a.u., arbitrary units; SD, standard deviation; HC, healthy controls; RRMS, relapsing-remitting multiple sclerosis.
Indicates statistical significance from linear regression models (adjusting for age and sex) (p < 0.05).