Table 2.
Process measures.
| PROCESS MEASURES | ||||||
|---|---|---|---|---|---|---|
| Measure | Baseline a | Post-Intervention |
Adjusted effect size & (95% CI): Baseline vs Post-intervention | |||
| All b | No Pathway c | With Pathway d | Adjusted effect size # (95% CI): No pathway vs with pathway | |||
| Lactate Measurement | 607 (82.9) | 997 (93.2) | 357 (87.1) | 640 (97.0) | 4.5 (2.7, 7.8) ** | 2.6 (1.9, 3.5) ** |
| Blood cultures before antibiotics | 596 (81.4) | 956 (89.3) | 342 (83.4) | 614 (93.0) | 2.6 (1.7, 3.8) ** | 1.9 (1.4, 2.5) ** |
| Two sets of blood cultures | 232 (31.7) | 782 (73.1) | 237 (57.8) | 545 (82.6) | 3.6 (2.7, 4.8) ** | 6.0 (4.8, 7.4) ** |
| Antibiotics within 3 hours of triage (sepsis alone) | 380 (61.5) | 630 (69.8) | 195 (55.6) | 435 (78.9) | 3.0 (2.2, 4.1) ** | 1.3 (1.1, 1.7) ** |
| Antibiotics within 1 hour of shock (septic shock) | 84 (73.7) | 143 (85.1) | 50 (84.7) | 93 (85.3) | 1.0 (0.4, 2.6) | 1.9 (1.1, 3.6) ** |
| IV fluid bolus within 1 hour (septic shock) | 50 (43.9) | 71 (42.3) | 25 (42.4) | 46 (42.2) | 1.0 (0.5, 2.0) | 1.0 (0.6, 1.6) |
| Compliance with 3-hour sepsis bundle (sepsis alone) | 298 (48.2) | 571 (63.3) | 157 (44.7) | 414 (75.1) | 3.8 (2.8, 5.1) ** | 1.7 (1.4, 2.1) ** |
| Compliance with 1-hour septic shock bundle (septic shock) | 48 (42.1) | 79 (47.0) | 24 (40.7) | 55 (50.5) | 1.7 (0.9, 3.4) | 1.2 (0.8, 2.0) |
CI confidence interval; IV intravenous; ICU intensive care unit.
n (%), effect estimate = odds ratio;
# post-intervention no pathway vs with pathway.
& baseline vs post-intervention;
a N (Baseline) All Sepsis = 732; Septic Shock = 114; Sepsis Alone = 618.
b N (Post-Intervention) All Sepsis = 1070; Septic Shock = 168; Sepsis Alone = 902.
c N (No Pathway) All Sepsis = 410; Septic Shock = 59; Sepsis Alone = 351.
d N (With Pathway) All Sepsis = 660; Septic Shock = 109; Sepsis Alone = 551.
** - 95% Confidence limits indicate a significant change.