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. 2021 Dec 8;11:623. doi: 10.1038/s41398-021-01737-5

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© This is a U.S. government work and not under copyright protection in the U.S.; foreign copyright protection may apply 2021

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Fig. 2 — Panel (A) shows repurposable compounds negatively associated with CUD gene expression in the brain (all p_adj < 0.05). Panel (B) shows the results of the medications currently undergoing clinical trials for CUD. The x-axis represents the weighted average of a compound’s correlation coefficients with the human brain CUD genes and each compound’s weighted standard error bars. Also, note that the black circles represent the effect across all brain regions/studies and the points below are color coded by brain region.