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. Author manuscript; available in PMC: 2023 Jan 1.
Published in final edited form as: J Allergy Clin Immunol. 2021 Jun 9;149(1):440–444.e2. doi: 10.1016/j.jaci.2021.05.037

Table 3.

Analysis of Vitamin D supplementation, compared with placebo, and change in total or allergen-specific IgE level between the exit and randomization visits.

Unadjusted
Adjusted
Parameter β 95% CI P β 95% CI P
Treatment
 Change in:
 Log10 total IgE (IU/mL) 0.011 −0.056 – 0.077 0.75 0.007 −0.061 – 0.074 0.85
 IgE to Der p (IU/ml) 1.467 −0.901 – 3.835 0.22 1.239 −1.170 – 3.648 0.31
 IgE to Bla g (IU/ml) 0.592 –0.341 – 1.525 0.21 0.501 −0.422 – 1.424 0.29
Treatment (in atopic subjects only [n=138])
 Change in:
 Log10 total IgE (IU/mL) 0.015 −0.051 – 0.081 0.65 0.012 −0.055 – 0.080 0.72
 IgE to Der p (IU/ml) 1.810 −1.188 – 4.808 0.23 1.297 −1.757 – 4.352 0.40
 IgE to Bla g (IU/ml) 0.755 −0.427 – 1.936 0.21 0.640 −0.520 – 1.801 0.28

Models adjusted for sex, race, study site, and time in the study.

Der p= Dermatophagoides pteronyssinus, Bla g= Blattella germanica

Atopy was defined as a total IgE ≥100 IU/ml or an IgE to Der p ≥0.35 IU/ml or an IgE to Bla g ≥0.35 IU/ml