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. 2021 Nov 25;12:779365. doi: 10.3389/fendo.2021.779365

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Copyright © 2021 Sun, Lu, Liu, Zhang, Wei, Hu, Hu, Zhao, Liu, Ye, Wang, Gu, Liu, Ye, Zhang, Zhu, Jiang, Liu, Wan, Yan, Yin, Ying, Huang, Yin, Xi, Luo and Cheng

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Annualized height velocity (HV) (A) and IGF-1 SD scores (SDS) (B) for PEGylated recombinant human growth hormone (PEG-rhGH) every other week (QOW), weekly PEG-rhGH (QW), and daily rhGH (QD) at baseline and weeks 4, 12, and 26. IGF-1 SDS change (C) at weeks 4, 12, and 26 from baseline for PEG-rhGH QOW, PEG-rhGH QW, and rhGH QD.