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. 2021 Nov 25;8:788545. doi: 10.3389/fmed.2021.788545

Table 4.

Multiple linear regression on dry eye disease and vision-related quality of life based on NEI-VFQ-25 in all the participants.

DED OSDI score Schirmer's I test (mm) TBUT (s)
95%CI 95%CI 95%CI 95%CI
β * P Low Up β* P Low Up β* P Low Up β* P Low Up
Overall −0.14 <0.01 −0.19 −0.09 −0.50 <0.01 −0.54 −0.45 0.01 0.69 −0.04 0.06 0.02 0.37 −0.03 0.08
General health −0.06 0.03 −0.11 −0.01 −0.11 <0.01 −0.16 −0.06 −0.05 0.06 −0.10 0.01 0.03 0.32 −0.03 0.08
General vision −0.18 <0.01 −0.24 −0.13 −0.39 <0.01 −0.44 −0.34 0.04 0.13 −0.01 0.09 0.05 0.06 <0.01 0.10
Ocular pain −0.02 0.49 −0.08 0.04 0.16 <0.01 0.11 0.22 0.01 0.88 −0.06 0.05 0.01 0.67 −0.04 0.07
Near activities −0.07 0.01 −0.12 −0.02 −0.24 <0.01 −0.29 −0.18 0.01 0.61 −0.04 0.07 0.01 0.95 −0.06 0.05
Distance activities −0.09 <0.01 −0.14 −0.03 −0.29 <0.01 −0.34 −0.24 0.02 0.38 −0.03 0.08 0.02 0.56 −0.04 0.07
Social functioning −0.07 0.02 −0.12 −0.01 −0.32 <0.01 −0.37 −0.26 −0.01 0.80 −0.06 0.05 0.02 0.56 −0.04 0.07
Mental health 0.05 0.11 −0.01 0.10 −0.14 <0.01 −0.19 −0.08 −0.02 0.44 −0.08 0.03 −0.04 0.20 −0.09 0.02
Role difficulties −0.05 0.06 −0.11 <0.01 −0.24 <0.01 −0.29 −0.18 0.02 0.49 −0.04 0.07 0.02 0.60 −0.04 0.07
Dependency −0.13 <0.01 −0.18 −0.07 −0.45 <0.01 −0.50 −0.40 0.05 0.08 −0.01 0.10 0.01 0.81 −0.05 0.06
Driving −0.10 0.02 −0.18 −0.02 −0.21 <0.01 −0.28 −0.15 −0.02 0.63 −0.10 0.06 0.01 0.98 −0.08 0.08
Color vision −0.01 0.70 −0.07 0.05 −0.21 <0.01 −0.27 −0.15 0.02 0.52 −0.04 0.07 0.01 0.80 −0.05 0.06
Peripheral vision −0.04 0.19 −0.09 0.02 −0.26 <0.01 −0.31 −0.20 −0.03 0.29 −0.09 0.03 0.01 0.94 −0.05 0.06

TBUT, Tear film break up time; OSDI, ocular surface disease index; CI, confidence interval; DED, dry eye disease; NEI-VFQ-25, 25-item National Eye Institute Visual Functioning Questionnaire.

*

Adjusted with age, gender, annual household incomes, and diabetes.

Bold values mean statistically significant.