Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Jun 11;34:79–91. doi: 10.1016/j.jare.2021.06.004

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2021 The Authors. Published by Elsevier B.V. on behalf of Cairo University. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

PMC Copyright notice

Fig. 7 — TA activates SHP-2 and regulates the expression of STAT3 target proteins in tumor tissue. (A) Tumor sections were subjected to H&E staining and IHC against Ki-67. Scale bars = 50 μm. ***P < 0.001 versus control group. (B) Representative images of p-STAT3 IHC staining. Scale bars = 50 μm. ***P < 0.001 versus control group. (C) Western blotting analysis of p-STAT3, STAT3, CyclinD1, p21, Bcl-2 in tumor tissues. (D) The samples from the tumor tissue on day 21 were used in detecting the tyrosine phosphatase activity of SHP-2. **P < 0.01, ***P < 0.001 versus control group.