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. 2021 Nov 25;8:790738. doi: 10.3389/fsurg.2021.790738

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Copyright © 2021 Koll, Meisenzahl, Haller, Maisch, Kirchhoff, Horn, Gschwend and Schmid.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Comparison of pre-operative biopsy to final pathology for pathologic staging and grading in all patients (A). Rate of patients being upstaged from pre-operative biopsy to final pathology. Seventy percent (64 patients) had concordant pathologic grading in URS biopsy and final pathology and 30% (28 patients) were upstaged from low grade to high grade. Sixty-two percent (58 patients) had pathologic upstaging from URS to final pathology, 37% (35 patients) had concordant pathologic stage. One patient had downstaging of pTa tumor in URS and no malignant residual tumor in RNU (B).