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. 2021 Nov 25;8:790738. doi: 10.3389/fsurg.2021.790738

Table 2.

Univariate Cox-regression model for overall survival.

Variable n Hazard ratio (95%CI) p
Age 151 1.07 (1.04–1.11) <0.0001
Sex Female vs. male 54 1.10 (0.66–1.83) 0.712
ECOG ≥2 vs. 0, 1 6 3.14 (1.23–8.03) 0.0167
Grading High-grade vs. low-grade 94 2.27 (1.18–4.35) 0.011
Tumor stage ≥pT2 vs. < pT2 74 3.45 (2.05–5.79) <0.0001
Lymph node metastases pN+ vs. pN0 25 5.13 (2.57–10.24) <0.0001
Resection margins R1/R2/Rx vs. R0 22 6.37 (3.58–11.36) <0.0001
Cis Cis vs. No Cis 25 1.77 (0.98–3.21) 0.06
Lymphovascular invasion Yes vs. No 29 2.96 (1.35–6.48) 0.0067
Localization Ureter vs. kidney pelvis vs. multiple 39 0.62 (0.32–1.22) 0.116
24 0.84 (0.42–1.66) 0.819
Lymphadenectomy Yes vs. No 86 0.97 (0.51–1.82) 0.751
Hydronephrosis Yes vs. No 75 1.19 (0.73–1.94) 0.487
Mitomycin C instillation Yes vs. No 26 0.30 (0.09–0.96) 0.0428
Bladder cuff excision Yes vs. No 122 0.37 (0.22–0.63) 0.00022

Bold and italics values indicate significant differences with p-values <0.05.