Figure 5.

A) Ionic strength affects the EDL configuration, which affects transduction between the MB reporter and the electrode. As the ionic strength of the solution increases, the Debye length (λ _D) decreases. Calibration curves were generated by performing SWV on aptamer‐functionalized B) planar and C) nanoporous electrodes with samples spiked with varying concentrations of DOX in different dilutions of SSC buffer to assess the impact of ionic strength on signal gain. Datapoints are averaged over three replicates, and error bars show standard deviation.