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. 2020 Dec 28;34:149–158. doi: 10.1016/j.jare.2020.12.010

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© 2021 The Authors. Published by Elsevier B.V. on behalf of Cairo University. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

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Fig. 4 — The cytotoxicity and effects of eugenol on complex I and mitochondrial membrane potential in PC12 and C6/36 cells. (a. The cytotoxicity of eugenol to PC12 and C6/36 cells. b: The effect of eugenol on the MMP in PC12 and C6/36 cells. c. Inhibitory effect of eugenol on complex I in PC12 and C6/36 cells. d. Molecular docking assay for determining the affinity of eugenol to A0A075XDS2 (mite) and P03891 peptides (human)). Asterisks indicate significant differences in the inhibition rates of cytotoxicity for a and from PC12 cells for c; n = 3, average ± SD, P < 0.05, independent samples t test.