Table 5.
Five- and 8-year bRFS of positive-margin patients stratified by RPA
| Variable | Level | n | 5 Year | 8 Year |
|---|---|---|---|---|
| RPA group | GG 1 & cumulative* ≤ 2.0 | 27 | 96% (76%-99%) | 92% (72%-98%) |
| GG 1 & cumulative > 2.0 | 49 | 71% (56%-82%) | 68% (52%-79%) | |
| GG 2 | 82 | 61% (49%-71%) | 50% (38%-62%) | |
| GG 3-5 & single max† < 3.0 | 20 | 49% (22%-71%) | 49% (22%-71%)‡ | |
| GG 3-5 & single max ≥ 3.0 | 26 | 21% (8%-38%) | 11% (2%-28%) |
Abbreviations: bRFS = biochemical relapse free survival; GG = Gleason grade; RPA = recursive partitioning by conditional inference analysis.
⁎
Cumulative margins.
†
Maximal extent of 1 involved margin.
‡
By 5 years, there are only 4 patients at risk still and none of them have had a failure by 8 years so it remains unchanged.