Table 1.
INF | PLC | PLC taSJC inactive | PLC taSJC active | PLC taCRP inactive | PLC taCRP active | Total | |
Patients (n) | 71 | 74 | 23 | 51 | 27 | 47 | 145 |
Age (years) | 47.7±12.5 | 46.8±11.1 | 46.2±10.2 | 47.0±11.5 | 47.5±11.9 | 46.4±10.7 | 47.2±11.7 |
Female (%) | 31.0 | 48.6 | 30.4 | 56.9 | 37.0 | 55.3 | 40.4 |
Disease duration (years) | 8.6±6.7 | 8.5±8.3 | 10.2±10.4 | 7.8±7.2 | 9.9±9.5 | 7.7±7.6 | 8.6±7.6 |
SJC (0–66) | 10.9±6.3 | 11.7±7.6 | 7.2±4.3 | 13.7±7.9 | 12.3±9.5 | 11.3±6.3 | 11.3±7.0 |
TJC (0–68) | 20.0±13.3 | 19.3±11.8 | 14.6±13.4 | 21.4±10.5 | 20.8±12.8 | 18.4±11.2 | 19.6±12.5 |
CRP (mg/dL) | 1.6±1.5 | 2.6±3.8 | 2.1±3.8 | 2.8±3.8 | 2.0±3.4 | 3.0±4.0 | 2.1±3.0 |
PGA (0–100 mm) | 52.5±20.7 | 60.2±22.7 | 53.1±25.6 | 63.3±20.8 | 61.0±24.5 | 59.8±21.8 | 56.4±22.0 |
EGA (0–100 mm) | 53.6±17.7 | 58.2±17.2 | 54.1±20.4 | 60.0±15.4 | 57.0±19.2 | 58.8±16.1 | 55.9±17.5 |
Pain (0–100 mm) | 54.9±21.6 | 59.7±23.2 | 51.4±27.0 | 63.3±20.6 | 61.1±24.2 | 58.8±22.8 | 57.3±22.5 |
DAPSA | 43.3±16.7 | 45.7±18.0 | 33.3±15.6 | 50.5±16.6 | 46.8±20.5 | 45.0±16.6 | 44.6±17.4 |
mTSS | 20.3±30.7 | 47.6±92.9 | 65.7±113.7 | 39.5±81.8 | 40.7±72.8 | 51.6±103.2 | 34.3±70.9 |
Data are shown as mean±SD unless indicated otherwise.
CRP, C reactive protein; DAPSA, Disease Activity in Psoriatic Arthritis; EGA, evaluator global assessment; INF, infliximab; mTSS, total modified Sharp/van-der-Heijde Score; PGA, patient global assessment; PLC, placebo; SJC, swollen joint count; taCRP, time-averaged C reactive protein; taSJC, time-averaged swollen joint count; TJC, tender joint count.