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. 2021 Dec 8;79(2):1–9. doi: 10.1001/jamapsychiatry.2021.3539

Table 2. Treatment Pathway and Outcomes.

Characteristic Treatment groupa Between-group comparisonsb P value
Stratified care (n = 583) Stepped care (n = 368)
Treatment pathway
LIT 251/583 (43.1) 261/368 (70.9) χ2 = 70.51 <.001
HITc 332/583 (56.9) 107/368 (29.1)
Treatment sessions, mean (SD) 7.10 (5.31) 5.84 (4.15) Mann-Whitney U test, 121106.00 (SE, 4098.98) <.001
Treatment dropout 166/542 (30.6) 107/348 (30.7) χ2 = 0.001 .97
Adherence to the stratified care model 523/583 (89.7) 233/368 (63.3) χ2 = 96.41 <.001
κ Statistic 0.81 0.22 NA NA
Treatment outcomes
PHQ-9 depression RCSI
Full sample 264/505 (52.3) 134/297 (45.1) 1.40 (1.04-1.87) .03
Complex cases subsample 63/160 (39.4) 22/65 (33.8) 1.28 (0.70-2.35) .42
Standard cases subsample 201/345 (58.3) 112/232 (48.3) 1.50 (1.07-2.09) .02
GAD-7 anxiety RCSI
Full sample 266/538 (49.4) 151/327 (46.2) 1.19 (0.90-1.57) .22
Complex cases subsample 52/160 (32.5) 21/65 (32.3) 1.02 (0.55-1.89) .96
Standard cases subsample 214/378 (56.6) 130/262 (49.6) 1.35 (0.98-1.85) .07
IAPT reliable recovery, full sampled 276/573 (48.2) 152/348 (43.7) 1.33 (1.01-1.75) .04

Abbreviations: GAD-7, Generalized Anxiety Disorder questionnaire; HIT, high-intensity treatments; IAPT, Improving Access to Psychological Therapies; LIT, low-intensity treatments; PHQ-9, 9-item Patient Health Questionnaire; RCSI, reliable and clinically significant improvement.

a

Unless otherwise indicated, data are expressed as number/total number (%) of patients.

b

Unless otherwise indicated, data are expressed as odds ratio (95% CI).

c

Of these, 46 (13.9%) had prior LIT in the stratified care group and 28 (7.6%) had prior LIT in the stepped care group.

d

Requires patients with case-level PHQ-9 and/or GAD-7 symptoms to have (1) attained statistically reliable improvement on case-level measures, (2) to have subclinical symptoms on both measures after treatment, and (3) to not have statistically reliable deterioration on any of these measures after treatment.