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. 2021 Oct 20;2(1):453–460. doi: 10.1089/neur.2021.0031

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© John B. Redell et al., 2021; Published by Mary Ann Liebert, Inc.

This Open Access article is distributed under the terms of the Creative Commons License [CC-BY] (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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FIG. 2. — Systemic IGF-2 administration does not improve object recognition memory in injured mice. (A) Experimental timeline. (B) Summary data (n = 7 per group) from the testing session showing that both vehicle- and IGF-2-treated, CCI-injured mice spent equivalent time exploring the familiar (F) and novel (N) objects, indicating that IGF-2 treatment had no effect on reversing injury-induced object recognition memory deficits. Data are presented as the mean ± SEM. CCI, controlled cortical impact; IGF-2, insulin-like growth factor-2; SEM, standard error of the mean.