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. 2021 Nov 25;9:757184. doi: 10.3389/fcell.2021.757184

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Copyright © 2021 Zhou, Wang, Ding, Yang and Xie.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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GO analysis and correlation analysis (A) GO analysis revealed the biological processes and molecular functions involved in the top 100 ATG5-related co-expressed genes by “metascape” data (B) The correlation between ATG5 and co-expressed genes involved in the regulation of the immune effector process in cervical cancer patients. Blue lines represent as negatively correlated genes, while red lines represent as positively correlated genes (C-J) Among those regulation of the immune effector process genes, ATG5 expression was significantly negatively correlated with MAP3K7, STX7 and significantly positively related to A2M, C1QA, C1QB, C1QC, RPS19, TYROBP, and IL20RB.