Table 5. Pharmacokinetic Parameters of Rottlerin after IV and Oral Administration at 1 and 4 mg/kg, Respectively, in Balb/C Mice.

parameters	unit	intravenous	oral
T1/2	h	2.9 ± 0.8	2.7 ± 0.4
C0	ng/mL	2111 ± 359.1
Cmax	ng/mL		660 ± 60.0
Tmax	h		2.4 ± 0.4
AUC0–t	ng h/mL	2849 ± 311.2	4054 ± 360.4
AUC0–∞	ng h/mL	2924 ± 292.4	4087 ± 347.8
Vd	L/kg	1.4 ± 0.4	3.8 ± 0.6
Cl	L/h/kg	0.35 ± 0.03	1.01 ± 0.08