TABLE 1.

Univariate and multivariate Cox regression analyses in each data set.

Variables	Univariate analysis			Multivariate analysis
	HR	95％ CI of HR	p-value	HR	95％ CI of HR	p-value
Training set
Risk score	2.718	1.995–3.703	<0.001	2.358	1.710–3.251	<0.001
Gender (male/female)	0.822	0.518–1.307	0.408	0.885	0.554–1.412	0.608
Stage (I/II/III/IV)	1.979	1.569–2.497	<0.001	1.706	1.345–2.163	<0.001
Age (<75/≥75)	2.067	1.188–3.597	0.010	1.812	1.036–3.170	0.037
Test set
Risk score	2.475	1.690–3.626	<0.001	2.590	1.735–3.865	<0.001
Gender (male/female)	0.851	0.481–1.506	0.580	0.882	0.485–1.601	0.679
Stage (I/II/III/IV)	1.254	0.911–1.727	0.164	1.296	0.930–1.807	0.126
Age (<75/≥75)	1.749	0.839–3.644	0.136	1.398	0.658–2.974	0.384