Table 2.

CASP checklist for assessing the body of the selected research articles [29]

	CASP questions
Q1	Is there a clear definition of the prediction model?
Q2	Does the dataset used to build predictive models sufficiently represent of the patient population?
Q3	Was the predictive model tested on a diverse patient group?
Q4	Were the outcome and the predictor variables examined in a blinded manner?
Q5	Were the evaluation of the outcome and the predictor variables performed on the whole sample that was initially selected?
Q6	Are the statistical approaches that were utilized to build and validate the predictive model described in detail?