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. 2021 Dec 9;21:1318. doi: 10.1186/s12885-021-09056-0

Table 2.

Univariate analysis of risks of OS

Univariate
HR P value
Age 1.012 (1.006–1.018) <0.001
Male 1.044 (0.932–1.170) 0.453
ALB 0.991 (0.981–1.002) 0.106
FBG 0.998 (0.992–1.004) 0.59
logCA199 1.318 (1.236–1.406) <0.001
TB 1.000 (1.000–1.001) 0.164
Biliary drainage 1.057 (0.929–1.203) 0.398
Body/tail 1.085 (0.971–1.212) 0.149
Diagnostic year 0.103
 2013 Ref.
 2014 1.029 (0.762–1.389) 0.852
 2015 1.204 (0.910–1.594) 0.194
 2016 0.937 (0.715–1.228) 0.637
 2017 1.120 (0.858–1.460) 0.405
 2018 1.153 (0.880–1.512) 0.301
 2019 0.960 (0.707–1.304) 0.795
ASA Score 0.798
 1 Ref.
 2 0.977 (0.867–1.102) 0.709
 3 0.926 (0.748–1.148) 0.485
 4 1.180 (0.707–1.968) 0.527
Stage <0.001
 Ia Ref.
 Ib 1.168 (1.508–1.946) 0.002
 IIa 1.618 (1.186–2.207) 0.002
 IIb 2.197 (1.717–2.811) <0.001
 III 3.213 (2.512–4.110) <0.001
 IV 6.307 (4.831–8.235) <0.001
Differentiation <0.001
 I Ref.
 II 2.645 (0.372–18.835) 0.331
 III 3.941 (0.554–28.008) 0.171
 IV 41.974 (2.616–673.418) 0.008
 Unknown 1.399 (0.127–15.446) 0.784
Chemotherapy 0.511 (0.458–0.570) <0.001
Surgical intervention 0.254 (0.207–0.309) <0.001
BMI 0.964 (0.946–0.983) <0.001
X-Tile categorizing <0.001
  < 18.9 Ref.
 18.9–23.3 0.745 (0.626–0.886) 0.001
  ≥ 23.3 0.665 (0.556–0.794) <0.001
WHO categorizing <0.001
  < 18.5 Ref.
 18.5–23 0.625 (0.514–0.759) <0.001
  ≥ 23 0.563 (0.462–0.685) <0.001

ALB Albumin, FBG Fasten blood glucose, TB Total bilirubin, HR Hazard ratio, Ref Reference