Table 3.
Multivariate analyses of risks of OS
| Continuous BMI | WHO Model | X-tile Model | ||||
|---|---|---|---|---|---|---|
| aHR | P value | aHR | P value | aHR | P value | |
| Age | 1.004 (0.998–1.011) | 0.223 | 1.004 (0.997–1.01) | 0.279 | 1.004 (0.997–1.011) | 0.234 |
| Male (female as Ref.) | 1.120 (0.992–1.266) | 0.068 | 1.124 (0.995–1.271) | 0.060 | 1.122 (0.993–1.268) | 0.064 |
| ALB | 1.004 (0.992–1.017) | 0.51 | 1.004 (0.992–1.016) | 0.541 | 1.005 (0.993–1.017) | 0.43 |
| FBG | 1.018 (0.997–1.039) | 0.086 | 1.017 (0.996–1.038) | 0.111 | 1.018 (0.998–1.039) | 0.084 |
| logCA199 | 1.164 (1.093–1.240) | <0.001 | 1.161 (1.09–1.236) | <0.001 | 1.162 (1.091–1.237) | <0.001 |
| TB | 1.000 (0.999–1.001) | 0.986 | 1 (0.999–1.001) | 0.902 | 1 (0.999–1.001) | 0.899 |
| Biliary drainage (no as Ref.) | 1.113 (0.941–1.316) | 0.213 | 1.109 (0.938–1.311) | 0.227 | 1.114 (0.942–1.318) | 0.205 |
| ASA Score | 0.142 | 0.163 | 0.151 | |||
| 1 | Ref. | Ref. | Ref. | |||
| 2 | 0.926 (0.817–1.050) | 0.231 | 0.926 (0.817–1.05) | 0.231 | 0.927 (0.818–1.051) | 0.239 |
| 3 | 1.182 (0.934–1.495) | 0.164 | 1.179 (0.931–1.493) | 0.171 | 1.184 (0.935–1.498) | 0.16 |
| 4 | 1.317 (0.753–2.305) | 0.334 | 1.272 (0.727–2.228) | 0.400 | 1.298 (0.742–2.271) | 0.36 |
| Stage | <0.001 | <0.001 | <0.001 | |||
| Ia | Ref. | Ref. | Ref. | |||
| Ib | 1.587 (1.210–2.080) | 0.001 | 1.58 (1.205–2.072) | 0.001 | 1.574 (1.2–2.064) | 0.001 |
| IIa | 1.704 (1.226–2.370) | 0.002 | 1.681 (1.209–2.337) | 0.002 | 1.691 (1.216–2.351) | 0.002 |
| IIb | 2.399 (1.846–3.117) | <0.001 | 2.384 (1.834–3.098) | <0.001 | 2.391 (1.84–3.107) | <0.001 |
| III | 3.568 (2.744–4.640) | <0.001 | 3.542 (2.724–4.607) | <0.001 | 3.558 (2.736–4.627) | <0.001 |
| IV | 6.478 (4.856–8.641) | <0.001 | 6.442 (4.831–8.591) | <0.001 | 6.501 (4.874–8.671) | <0.001 |
| Differentiation | <0.001 | <0.001 | <0.001 | |||
| I | Ref. | Ref. | Ref. | |||
| II | 4.642 (0.649–33.205) | 0.126 | 4.725 (0.66–33.815) | 0.122 | 4.762 (0.665–34.092) | 0.12 |
| III | 6.444 (0.903–46.008) | 0.063 | 6.562 (0.918–46.882) | 0.061 | 6.637 (0.929–47.436) | 0.059 |
| IV | \ | \ | \ | \ | ||
| Unknown | 1.652 (0.147–18.599) | 0.684 | 1.744 (0.155–19.613) | 0.652 | 1.744 (0.155–19.61) | 0.652 |
| Chemotherapy | 0.458 (0.405–0.518) | <0.001 | 0.462 (0.408–0.522) | <0.001 | 0.462 (0.408–0.522) | <0.001 |
| BMI | 0.972 (0.953–0.991 | 0.004 | ||||
| BMI Stage | 0.002 | 0.003 | ||||
| Underweight | Ref. | Ref. | ||||
| Normal | 0.759 (0.617–0.935) | 0.010 | 0.821 (0.682–0.989) | 0.038 | ||
| Overweight | 0.685 (0.555–0.847) | 0.000 | 0.723 (0.597–0.875) | 0.001 | ||
ALB Albumin, FBG Fasten blood glucose, TB Total bilirubin, aHR Adjusted hazard ratio, Ref Reference