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. 2021 Dec 9;7:60. doi: 10.1186/s40813-021-00241-y

Table 5.

Effects of dietary treatment1 on cytokine expression in tissues of piglets at different time points

Day Tissue IFN-α IFN-γ IL-1α IL-1β IL-6 IL-8 IL-10 IL-12α IL-12 β TNF-α TGF-β
15 Jejunum  < *  < *  < ^  < ^  < *  < ^
Ileum
Colon  < ^  < ^
PBMC  > *  > *  > ^  > *  > ^  > *  > *  > *  > ^  > *
30 Jejunum  > ^  < ^
Ileum  < ^
Colon  > *  > ^
PBMC  > ^
45 Jejunum  < *  < *  < *
Ileum  > *
Colon  < ^  < *  < ^
PBMC  < *

(*) Significant (P < 0.05) and (^) tendency (P < 0.1) upregulation ( >) or downregulation ( <) of cytokine mRNA levels of FS compared to control

1Dietary treatment = additional Fysal Solute (FS) at 2 kg/ton