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. Author manuscript; available in PMC: 2021 Dec 9.
Published in final edited form as: Clin Cancer Res. 2014 May 29;20(14):3753–3762. doi: 10.1158/1078-0432.CCR-13-3042

Table 2.

Histological and immunohistochemical analysis of oral MM from dogs included in the study

Threshold Overall population Group I Group II Group III Group II+ III
Ki67 a < 19.5 18.5% (27/33)b 9.1% (11/14)b 18.2% (11/13)b 40.0% (5/6)b 25.0% (16/19)b
≥ 19.5 81.5% (27/33) 90.9% (11/14) 81.8% (11/13) 60.0% (5/6) 75.0% (16/19)
Mitotic Index (MI) a < 4/10 hpf 3 (9.1%) 3 (21.4%) 0 (0.0%) 0 (0.0%) 0 (0.0%)
≥ 4/10 hpf 30 (90.9%) 11 (78.6%) 13 (100.0%) 6 (100.0%) 19 (100.0%)
Nuclear Atypia (PLEOM) a < 30.0%
≥ 30.0%
14 (42.4%)
19 (57.6%)
5 (35.7%)
9 (64.3%)
5 (38.5%)
8 (61.5%)
4 (66.7%)
2 (33.3%)
9 (47.4%)
10 (52.6%)
a

prognostic factors for cMM as proposed by Bergin et al. (32), Smedley et al. (33), Ottnod et al. (25)

b

number of patients for which the data were available