Table 3.
Relationship between variables and BMs by univariate and multivariate logistic regression analyses.
| Characteristics | Univariate logistics regression | Multivariable logistics regression | ||||
|---|---|---|---|---|---|---|
| OR | 95% CI | p-value | OR | 95% CI | p-value | |
| Age | 1.02 | 1.01–1.02 | <0.001 | 1 | 1–1.01 | 0.052 |
| Sex | ||||||
| Female | Ref | Ref | Ref | Ref | Ref | Ref |
| Male | 1.31 | 1.19–1.45 | <0.001 | 1.23 | 1.1–1.38 | <0.001 |
| Race | ||||||
| Black | Ref | Ref | Ref | Ref | Ref | Ref |
| White | 1.32 | 1.14–1.54 | <0.001 | 1.11 | 0.93–1.32 | 0.242 |
| Chinese | 1.53 | 1.02–2.30 | 0.04 | 1.28 | 0.81–2.01 | 0.293 |
| Other | 1.17 | 0.94–1.46 | 0.161 | 0.91 | 0.71–1.18 | 0.485 |
| Marital | ||||||
| Married | Ref | Ref | Ref | Ref | Ref | Ref |
| Unmarried | 1.19 | 1.08–1.3 | <0.001 | 1.04 | 0.93–1.16 | 0.507 |
| Unknown | 0.74 | 0.58–0.95 | 0.016 | 0.77 | 0.58–1.01 | 0.063 |
| Sequence number | ||||||
| More than 1 | Ref | Ref | Ref | Ref | Ref | Ref |
| 1 primary only | 1.93 | 1.73–2.16 | <0.001 | 1.49 | 1.31–1.69 | <0.001 |
| Primary site | ||||||
| Kidney | Ref | Ref | Ref | Ref | Ref | Ref |
| Renal pelvis | 0.77 | 0.61–0.97 | 0.029 | 0.44 | 0.27–0.73 | 0.002 |
| Laterality | ||||||
| Left | Ref | Ref | Ref | Ref | Ref | Ref |
| Right | 0.94 | 0.85–1.03 | 0.16 | 1.03 | 0.93–1.14 | 0.611 |
| Other | 7.78 | 4.84–12.5 | <0.001 | 2.36 | 1.32–4.19 | 0.004 |
| Grade | ||||||
| Moderately | Ref | Ref | Ref | Ref | Ref | Ref |
| Well | 0.51 | 0.31–0.85 | 0.009 | 0.58 | 0.35–0.96 | 0.036 |
| Poorly | 3.17 | 2.58–3.89 | <0.001 | 1.96 | 1.59–2.43 | <0.001 |
| Undifferentiated | 7.62 | 6.16–9.41 | <0.001 | 3.02 | 2.39–3.83 | <0.001 |
| Unknown | 11.8 | 9.91–14.05 | <0.001 | 5.33 | 4.39–6.47 | <0.001 |
| Histology | ||||||
| Transitional cell carcinoma | Ref | Ref | Ref | Ref | Ref | Ref |
| Papillary transitional cell carcinoma | 0.12 | 0.06–0.24 | <0.001 | 0.34 | 0.17–0.67 | 0.002 |
| Papillary adenocarcinoma | 0.15 | 0.11–0.21 | <0.001 | 0.31 | 0.18–0.51 | <0.001 |
| Clear-cell adenocarcinoma | 0.47 | 0.38–0.6 | <0.001 | 0.8 | 0.51–1.25 | 0.317 |
| Renal cell carcinoma | 1.18 | 0.93–1.49 | 0.167 | 0.71 | 0.45–1.12 | 0.138 |
| Renal cell carcinoma, chromophobe type | 0.14 | 0.09–0.21 | <0.001 | 0.22 | 0.12–0.41 | <0.001 |
| Other | 1.43 | 1.11–1.85 | 0.006 | 0.95 | 0.61–1.5 | 0.838 |
| T (tumor invasion) | ||||||
| T1 | Ref | Ref | Ref | Ref | Ref | Ref |
| T2 | 4.36 | 3.8–5.01 | <0.001 | 2.01 | 1.69–2.4 | <0.001 |
| T3 | 3.76 | 3.34–4.24 | <0.001 | 1.72 | 1.47–2 | <0.001 |
| T4 | 11.17 | 9.41–13.27 | <0.001 | 1.99 | 1.59–2.5 | <0.001 |
| TX | 18.44 | 15.6–21.79 | <0.001 | 2.71 | 2.19–3.36 | <0.001 |
| N (regional lymph node) | ||||||
| N0 | Ref | Ref | Ref | Ref | Ref | Ref |
| N1 | 10.14 | 9.07–11.32 | <0.001 | 2.16 | 1.88–2.48 | <0.001 |
| N2 | 4.73 | 3.1–7.23 | <0.001 | 3.11 | 1.78–5.43 | <0.001 |
| NX | 5.21 | 4.47–6.08 | <0.001 | 1.67 | 1.37–2.02 | <0.001 |
| Tumor size | 1.01 | 1.01–1.01 | <0.001 | 1.00 | 1.00–1.00 | 0.741 |
| Brain metastasis | ||||||
| No | Ref | Ref | Ref | Ref | Ref | Ref |
| Yes | 15.05 | 12.58–18.01 | <0.001 | 2.36 | 1.91–2.92 | <0.001 |
| Unknown | 48.7 | 27.23–87.10 | <0.001 | 3.98 | 1.95–8.11 | <0.001 |
| Liver metastasis | ||||||
| No | Ref | Ref | Ref | Ref | Ref | Ref |
| Yes | 15.96 | 13.95–18.28 | <0.001 | 2.34 | 1.99–2.75 | <0.001 |
| Unknown | 32.97 | 20.66–52.63 | <0.001 | 2.91 | 1.61–5.27 | <0.001 |
| Pulmonary metastasis | ||||||
| No | Ref | Ref | Ref | Ref | Ref | Ref |
| Yes | 18.9 | 17.12–20.86 | <0.001 | 4.31 | 3.81–4.88 | <0.001 |
OR, odds ratio; 95% CI, 95% confidence interval.