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. 2021 Nov 25;9:795150. doi: 10.3389/fchem.2021.795150

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Copyright © 2021 Lin, Zhang, Liu, Ye, Chen, Huang, Zeng, Liao, Zhan, Zhou and Cao.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Combination of quercetin and colistin contributes to the damage of bacterial cell membranes and the leakage of bacterial ALPs. The absorbance at 510 nm integrity of E. coli (A) and K. pneumoniae (B) by detecting ALP. The chart indicates that an increase for alkaline phosphatase in the medium after exposure to the specified compound. The results are shown as the mean and standard deviation of three independent experiments. ns stands for not significant, *p < 0.05, **p < 0.01, ***p < 0.001, determined by the Student’s t-test.