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Recovery and matrix effect of alpelisib in rat plasma (n = 6).
| Analyte | Concentration added (ng/ml) | Recovery (%) | Matrix effect (%) | ||
|---|---|---|---|---|---|
| Means ± SD | RSD (%) | Means ± SD | RSD (%) | ||
| 2 | 89.5 ± 3.2 | 3.6 | 103.0 ± 5.7 | 5.5 | |
| Alpelisib | 800 | 90.9 ± 1.4 | 1.6 | 100.1 ± 2.3 | 2.3 |
| 4,000 | 94.9 ± 2.5 | 2.7 | 96.7 ± 5.0 | 5.2 | |
