TABLE 2.

Summary of CoMFA and CoMSIA models.

PLS statistics	CoMFA	CoMSIA
q2	0.81	0.82
N	6	6
r2	0.97	0.96
F	258.06	228.71
$r_m^2$	0.78	0.79
$r_{pred}^2$	0.89	0.89
SDEPext	0.22	0.23
SEE	0.11	0.11
Steric	0.81	0.20
Electrostatic	0.19	0.22
Hydrophobic	-	0.40
Hydrogen bond acceptor	-	0.18