Skip to main content
. 2021 Dec 6;9(1):e1119. doi: 10.1212/NXI.0000000000001119

Figure 2. ULBP4 Is Mainly Expressed by Astrocytes in Brain Tissue From Patients With MS and Controls.

Figure 2

(A) Representative images for the costaining of ULBP4 (cyan) and GFAP (magenta) in paraffin-embedded sections from untreated MS donors (NAGM and WM lesion) and controls (no brain related disease); n = 4 for each group. Nuclei were stained with 4',6-diamidino-2-phenylindole (blue). Corresponding isotype controls are shown. Yellow arrows indicate ULBP4+GFAP+ cells, and red arrows indicate ULBP4-negative GFAP+ cells. Scale bars = 25 μM. (B) Representative enlarged image showing colocalization of GFAP and ULBP4 in the brain section. Scale bars = 10 µM. GFAP = glial fibrillary acidic protein; MS = multiple sclerosis; NAGM = normal-appearing gray matter; WM = white mater; ULBP4 = UL16-binding protein 4.