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. 2021 Nov 25;12:700933. doi: 10.3389/fimmu.2021.700933

Figure 2.

Figure 2

Loss of JNK2 worsens lung inflammation and injury during pseudomonas pneumonia. Wild-type and JNK2 KO mice were subjected to i.n. pseudomonas aeruginosa (strain PA103)-induced pneumonia. (A) Mortality of PA103-treated wild-type and JNK2 KO mice. N=9-10. (B–E) Cell count and protein content (B) and neutrophil count (C) in BAL fluid, and mRNA expressions of inflammatory cytokines from whole lung homogenates (D), or sectional lung histology (E) from PBS- or PA103-treated mice. In (B), PBS: N=3-8; PA103: N=13-14. In (C), N=3-4. In (D), PBS: N=3; PA103: N=4-5. Data are presented as means ± sem. *p < 0.05; **p < 0.01.