Table 1.

SARS-CoV-2 variants showing enrichment epitope mutation rate.

Supertype	SARS-CoV-2			% epitope	% control peptide	Epitope/control
	Top Lineage	Variant a	Top Location	mutation rate	mutation rate	mutation rate ratio
A01	B.1.1.7	69X_70X_144X_367F_501Y	45 Scotland	13.02	1.64	7.94
A01	A.23.1	367F_681R	112 Uganda	11.27	1.64	6.87
A01 A03	C.36	69X_70X_346S_452R	61 England	27.50	0.78	35.26
A01 A03	B.1.1.7	69X_70X_144X_384L_501Y	108 England	15.00	1.56	9.62
A01 A03	B.1.525	5F_144X_484K	73 New York	15.00	1.56	9.62
A01 A24	B.1.427	452R_503I	51 Minnesota	14.53	0.00	–
A01 A24	A.23.1	367F_681R	112 Uganda	12.35	0.90	13.72
A01 A24	B.1.525	144X_452R	152 New York	10.73	0.90	11.92
A01 A24	B.1.1.7	69X_70X_144X_367F_501Y	45 Scotland	11.88	1.80	6.60
A01 A24	B.1.617.2	452R_478K_681R	1029 England	10.73	1.80	5.96
A02	B.1	242X_243X_244X_417N_501Y	97 Turkey	8.68	0.00	–
A02	P.1	18F_417T	19 Massachusetts	9.62	1.45	6.63
A03	B.1.1.7	69X_70X_144X_354D_501Y	109 England	19.83	0.00	–
A24	B.1.525	144X_452R	152 New York	7.92	0.00	–
A24	A	449H_501Y	51 England	7.67	0.00	–
A24	B.1.427	452R_522P	195 Michigan	9.95	1.18	8.43
B07	B.1.1.7	69X_70X_144X_501Y	300 England	26.81	1.39	19.29
B27	B.1	242X_243X_244X_417N_501Y	97 Turkey	20.17	0.00	–
B27	B.1.525	144X_452R	152 New York	12.44	1.54	8.08
B27	B.1.351	18F_242X_243X_244X_417N_484K_501Y	255 Mamoudzou	24.04	3.08	7.81
B44	A.23.1	367F_681R	112 Uganda	10.61	0.00	–
B58	C.36	69X_70X_346S_452R	61 England	9.15	1.19	7.69
B62	B.1	242X_243X_244X_417N_501Y	97 Turkey	9.70	0.00	–
B62	B.1.1.7	69X_70X_144X_501Y	300 England	13.86	2.00	6.93
B62	B.1.351	18F_242X_243X_244X_417N_484K_501Y	255 Mamoudzou	11.88	2.00	5.94

^aVariants carrying >5% epitope mutation rate for at least one supertype, besides no mutated control epitope or >5-fold enrichment respect to background peptides are shown. Only the top variant per lineage is selected.