Figure 3. Biomarker analysis by liquid biopsy.
Biomarker analysis of BRAF-V600E in CSF (upper panel) and plasma (lower panel): cfDNA separated on the Agilent 2100 Bioanalyzers with an HS DNA chip. Fragment length distribution shows mono-, di-, and tri-nucleosomal peaks, as well as high molecular weight DNA.
CSF, cerebrospinal fluid; cfDNA, cell-free DNA; HS, high sensitivity