Evidence on in vitro maturation

Presently, no robust data for comparison

The retrieval of in vivo matured oocytes, implantation and pregnancy rates of IVM are less than expected in comparison to conventional ART

Priming with hCG and/or FSH appears to improve implantation and pregnancy rates compared to no priming[20]

IVM should only be performed as an experimental procedure in specialized centers for carefully selected patients evaluating both efficacy and safety. Informed consent must include information regarding pregnancy rates of IVM in comparison to conventional ART and alternative options if any[22]

IVM=In vitro maturation, ART=Assisted reproductive technologies, hCG=Human chorionic gonadotropin, FSH=Follicle-stimulating hormone