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. 2021 Nov 25;12:738812. doi: 10.3389/fmicb.2021.738812

TABLE 5.

CFR values for three antibiotics against CRE.

Antimicrobials Dosing regimens CFR (%)
Tigecycline 50 mg every 12 h 73.42
75 mg every 12 h 85.32
100 mg every 12 h 91.88
Polymyxin B 1.25 mg/kg every 12 h 81.14
1.5 mg/kg every 12 h 82.69
2.5 mg/kg per day continuous infusion 80.89
Ceftazidime/avibactam 1.25 g every 8 h 66.59
2.5 g every 8 h 77.42

CFR, cumulative fraction of response; CRE, carbapenem-resistant Enterobacterales.