TABLE 2.

Top 20 highly expressed genes in the mid-exponential growth phase of strain ST7.

No.	Gene-ID	Mean-control	Mean-Mn (II)	logFC	Up/down	Protein_ID	Product	Group from	KAAS path
1	RS10445	88280.22	141677.22	0.22	no-diff	WP_024422684.1	aldehyde dehydrogenase family protein	Mn (II) presence	Carbohydrate metabolism
2	RS11640	100730.83	176474.87	0.35	no-diff	WP_024422883.1	tetratricopeptide repeat protein	both	Cellular community – prokaryotes, Quorum sensing
3	RS00700	104162.21	130477.58	–0.16	no-diff	WP_024425592.1	DNA-directed RNA polymerase subunit beta′	both	Genetic Information Processing, Transcription
4	RS00695	91830.33	104047.58	–0.30	no-diff	WP_024425866.1	DNA-directed RNA polymerase subunit beta	Mn (II) presence	Genetic Information Processing, Transcription
5	RS16485	49900.61	92696.21	0.36	no-diff	WP_044331271.1	acyl-CoA dehydrogenase	Mn (II) presence	Lipid metabolism
6	RS14625	304383.81	293470.15	–0.51	no-diff	WP_073206977.1	fatty acid desaturase	both	Lipid metabolism, Lipid biosynthesis proteins
7	RS00720	42836.31	112770.20	0.89	no-diff	WP_024425594.1	elongation factor G	Mn (II) presence	genetic information processing, Translation factors
8	RS16905	709030.83	686287.16	–0.52	no-diff	tmRNA	transfer-messenger RNA	both
9	RS00140	542029.69	658780.54	–0.19	no-diff	ncRNA	signal recognition particle sRNA large type	both
10	RS04460	68343.95	97151.59	0.07	no-diff	WP_012009371.1	hypothetical protein	Mn (II) presence
11	RS09610	8147.14	106043.44	3.23	up	WP_024425140.1	aconitate hydratase AcnA	Mn (II) presence	Carbohydrate metabolism
12	RS09515	22869.93	136468.06	2.12	up	WP_024425124.1	trypsin-like serine protease	Mn (II) presence	Cellular community – prokaryotes, Quorum sensing
13	RS16495	33687.41	97529.70	1.03	up	WP_044331273.1	3-hydroxyacyl-CoA dehydrogenase	Mn (II) presence	Lipid metabolism
14	RS03925	7328.75	172637.44	4.15	up	WP_024425256.1	hypothetical protein	Mn (II) presence
15	RS14680	585070.82	249768.46	–1.69	down	WP_024424829.1	alpha/beta-type small acid-soluble spore protein	both	cellular processes, Cell growth, sporulation
16	RS11215	514610.92	158678.55	–2.15	down	WP_008344534.1	stage IV sporulation protein A	both	cellular processes, Cell growth, sporulation
17	RS04855	263511.07	118772.43	–1.59	down	WP_024425744.1	alpha/beta-type small acid-soluble spore protein	both	cellular processes, Cell growth, sporulation
18	RS13255	290406.13	102815.80	–1.96	down	WP_073206510.1	SafA/ExsA family spore coat assembly protein	both	cellular processes, Cell growth, sporulation
19	RS05125	372823.66	110835.29	–2.19	down	WP_044335827.1	S8 family serine peptidase	both	Protein metabolism
20	RS10900	300404.97	182576.48	–1.20	down	ncRNA	RNase P RNA component class B	both
21	RS04210	159812.20	81786.51	–1.41	down	WP_012009334.1	gamma-type small acid-soluble spore protein	Mn (II) presence	cellular processes, Cell growth, sporulation
22	RS08325	133133.55	50844.61	–1.83	down	WP_024424105.1	outer spore coat protein CotE	Mn (II) presence	cellular processes, Cell growth, sporulation
23	RS13665	144372.34	50222.53	–1.99	down	WP_073206706.1	LysM peptidoglycan-binding domain-containing protein	Mn (II) presence	cellular processes, Cell growth, sporulation
24	RS18780	114554.98	49633.09	–1.66	down	WP_024426405.1	spore coat protein GerQ	Mn (II) presence	cellular processes, Cell growth, sporulation
25	RS04580	101499.85	43091.09	–1.69	down	WP_034623898.1	YhcN/YlaJ family sporulation lipoprotein	Mn (II) presence	cellular processes, Cell growth, sporulation
26	RS04525	225740.47	68288.06	–2.17	down	WP_024425326.1	PrkA family serine protein kinase	Mn (II) presence	signaling
27	RS12630	108308.45	28956.33	–2.35	down	WP_024423047.1	late competence protein ComER	Mn (II) presence	signaling and cellular processes, Secretion system
28	RS02490	110584.14	37469.98	–2.01	down	WP_087975235.1	outer membrane lipoprotein carrier protein LolA	Mn (II) presence
29	RS04895	99559.03	28529.70	–2.26	down	WP_039177545.1	Cof-type HAD-IIB family hydrolase	Mn (II) presence