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. 2021 Nov 25;12:760476. doi: 10.3389/fmicb.2021.760476

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Copyright © 2021 Seo, Seong, Kim, Jo, Cheon, Song, Ryu, Kang and Han.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Effects of Limosilactobacillus reuteri EFEL6901 strain on improvement of symptoms in DSS-induced murine colitis model. The body weight (A) and the disease activity index score (B) were evaluated throughout the experiment. After 15 days, the mice were sacrificed and colon lengths (C,D) were measured. (E) Histological features of a representative colon of each group. m, mucosa; sm, submucosa; mm, muscular layer. Mag. = X100 for all. (F) The histological score combining inflammatory cell infiltration and loss of intestinal glands. Results are expressed as means ± standard error (n = 7). Significant differences are presented with the DSS group: *p < 0.05; **p < 0.01.