Table 1.
Sample characteristics.
| Time 1 (n = 146) |
Time 2 (n = 58) |
|
|---|---|---|
| Age (years), mean (SD; min–max) | 68 (9.6; 35–80) | 69 (8.9; 46–84) |
| Female gender, n (%) | 67 (46) | 32 (55) |
| PD duration (years), mean (SD; min–max) | 4.0 (3.9; 0.1–17.0) | 7.0 (3.7; 3.6–20) |
| PD severity (HY), median (q1–q3; min–max) | 2 (2–3; 1–4) | 2 (2–3; 1–4) |
| Daily total levodopa equivalent (LDE) dose (mg), median (q1–q3; min–max) | 400 (300−600; 0–1477) | 500 (400–675; 150–1580) |
| Self-rated motor status at the time of clinical examination “on” or “on with dyskinesias,” n (%) “off,” n (%) |
128 (88) 18 (12) |
48 (83) 10 (17) |
| Motor symptoms (UPDRS part III), median (q1–q3; min–max) | 12 (8–18; 1–46) | 13.5 (9–20; 1–40) |
| Cognition (MMSE), median (q1–q3; min–max) | 28 (26–29; 19–30) | 28 (27–29; 20–30) |
| Retropulsion (NRT), median (q1–q3; min–max) | 0 (0–1; 0–2) | 0 (0–1; 0–3) |
| Retropulsion (UPDRS30), median (q1–q3; min–max) | 0 (0–1; 0–2) | 0 (0–1; 0–3) |
HY, Hoehn and Yahr; MMSE, Mini-Mental State Examination; NRT, Nutt Retropulsion Test; PD, Parkinson’s disease; UPDRS, Unified Parkinson’s Disease; Rating Scale; UPDRS part III, motor score of the Unified Parkinson’s Disease Rating Scale; UPDRS30, item 30 of UPDRS.